Cotinine Test Strips
Cotinine Test Strip is the first-stage metabolite of nicotine. A toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans.
Nicotine is a drug to which virtually every member of a tobacco-smoking. Society exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies. Such as nicotine gum, transdermal patches, and nasal sprays.
In a 24-hour urine, approximate 5% of a nicotine dose excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine. The concentrations of other metabolites believed to account for less than 5%. While cotinine thought to an inactive metabolite. its elimination profile is stable than that of nicotine largely urine pH-dependent. As a result, cotinine considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximate 60 minutes following inhalation or parenteral administration. Nicotine and cotinine rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 200 ng/mL expected to be up to 2-3 days after nicotine use.
12 Panel Medical offers multi-panel drug screen tests that test for cocaine in urine as well as urine test strips. That test specifically for the use of this illicit drug and its metabolites. Cocaine drug test strips are 99% accurate, and urinalysis for cocaine use is one of the most common methods of testing due to a significantly small rate of false positives. Immunoassay urine drug testing for cocaine is effective, efficient. Easy enough for at home use but graded for clinical settings.
Cotinine Test Strip is one of the most common drugs tested for. It appears on most standard multi-screen drug panels tests. Cocaine drug tests may be used in:
- Workplace drug screening programs
- Approval for insurance applications
- Probation and parole terms
- The situation where driving under the influence is suspected
- Substance abuse monitoring
- An emergency room situation where drug abuse is suspected
With qualitative and definite results in five minutes, urine test strips can operate without formal training. Individuals may consider testing for cocaine use to monitor substance abuse in someone in the home.
Cotinine Test Strip involves identifying both the parent drug as well as its metabolites. Cotinine drug tests that identify Cotinine in urine detect both of these metabolites. The parents drug in compliance with cutoff concentrations as set by SAMHSA. Cutoff concentrations expressed in nanograms per milliliter and set at 300 ng/ml to determine if cocaine is abused.
A sample urine specimen must collect from the donor for testing. When the urine specimen is ready for testing, the operator will remove the cocaine use test strip from the protective packaging.
The testing strip may damage by extended exposure to light and air. Do not remove the strip until ready to perform the test to ensure the most reliable results. If the testing strip removed from packaging than 1 hour prior to testing, the results should not interpreted.
Do not touch the strip membrane. Bacteria from hands and surfaces may contaminate the testing strip and invalidate results.
Hold the cocaine drug test strip where the product name printed. Carefully place the testing strip membrane into the cup, in a vertical position. Do not immerse the strip past the MAX line on the testing strip.
Allow the strip to absorb as much of the sample as possible, immersing the membrane in the specimen for at least 10 to 15 seconds. You might notice color moving across the strip. But the results cannot read before five minutes. Do not interpret results after 10 minutes.
If the specimen contains more than the pre-determined cutoff levels, the result is positive. This indicated by one colored band in the control region and no colored band in the test region. Positive results should send to a toxicology laboratory for confirmation.
A negative result indicated by one colored band in the control region. One colored band in the test region. A negative result indicates that the specimen does not reach the cutoff levels.
If no colored band appears in the control indicator of the test strip, the result is invalid. The test must perform again. If the problem persists. Then you may contact your local distributor.